1zwk

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|PDB= 1zwk |SIZE=350|CAPTION= <scene name='initialview01'>1zwk</scene>, resolution 2.60&Aring;
|PDB= 1zwk |SIZE=350|CAPTION= <scene name='initialview01'>1zwk</scene>, resolution 2.60&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE ION'>PO4</scene>
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|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>
|ACTIVITY=
|ACTIVITY=
|GENE= wrba ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])
|GENE= wrba ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])
 +
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK03767 PRK03767]</span>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zwk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zwk OCA], [http://www.ebi.ac.uk/pdbsum/1zwk PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1zwk RCSB]</span>
}}
}}
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[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
[[Category: Shapiro, L.]]
[[Category: Shapiro, L.]]
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[[Category: PO4]]
 
[[Category: new york structural genomix research consortium]]
[[Category: new york structural genomix research consortium]]
[[Category: nysgxrc]]
[[Category: nysgxrc]]
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[[Category: wrba]]
[[Category: wrba]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:40:44 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:18:57 2008''

Revision as of 04:18, 26 March 2008


PDB ID 1zwk

Drag the structure with the mouse to rotate
, resolution 2.60Å
Ligands:
Gene: wrba (Pseudomonas aeruginosa)
Domains: PRK03767
Resources: FirstGlance, OCA, PDBsum, JenaLib, RCSB
Coordinates: save as pdb, mmCIF, xml



Structure of WrbA from Pseudomonas aeruginosa


Overview

The tryptophan repressor binding protein WrbA binds to the tryptophan repressor protein TrpR. Although the biological role of WrbA remains unclear, it has been proposed to function in enhancing the stability of TrpR-DNA complexes. Sequence database analysis has identified WrbA as a founding member of a flavodoxin-like family of proteins. Here we present crystal structures of WrbA from Deinococcus radiodurans and Pseudomonas aeruginosa and their complexes with flavin mononucleotide. The protomer structure is similar to that of previously determined long-chain flavodoxins; however, each contains a conserved inserted region unique to the WrbA family. Interestingly, each WrbA protein forms a homotetramer with 222 symmetry, unique among flavodoxin-like proteins, in which each protomer binds one flavin mononucleotide cofactor molecule.

About this Structure

1ZWK is a Single protein structure of sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.

Reference

Crystal structures of the tryptophan repressor binding protein WrbA and complexes with flavin mononucleotide., Gorman J, Shapiro L, Protein Sci. 2005 Dec;14(12):3004-12. PMID:16322580

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