292d

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|PDB= 292d |SIZE=350|CAPTION= <scene name='initialview01'>292d</scene>, resolution 1.000&Aring;
|PDB= 292d |SIZE=350|CAPTION= <scene name='initialview01'>292d</scene>, resolution 1.000&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=P24:1-(AMINOETHYL)AMINO-4-AMINOBUTANE'>P24</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=NA:SODIUM ION'>NA</scene>
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|LIGAND= <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=P24:1-(AMINOETHYL)AMINO-4-AMINOBUTANE'>P24</scene>
|ACTIVITY=
|ACTIVITY=
|GENE=
|GENE=
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|DOMAIN=
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=292d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=292d OCA], [http://www.ebi.ac.uk/pdbsum/292d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=292d RCSB]</span>
}}
}}
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[[Category: Tomita, K.]]
[[Category: Tomita, K.]]
[[Category: Wang, A H.J.]]
[[Category: Wang, A H.J.]]
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[[Category: MG]]
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[[Category: complexed with n-(2-aminoethyl)-1,4-diaminobutane]]
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[[Category: NA]]
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[[Category: P24]]
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[[Category: 4-diaminobutane]]
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[[Category: complexed with n-(2-aminoethyl)-1]]
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[[Category: double helix]]
[[Category: double helix]]
[[Category: z-dna]]
[[Category: z-dna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:43:44 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:46:00 2008''

Revision as of 22:46, 30 March 2008


PDB ID 292d

Drag the structure with the mouse to rotate
, resolution 1.000Å
Ligands: , , , ,
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



INTERACTION BETWEEN THE LEFT-HANDED Z-DNA AND POLYAMINE:THE CRYSTAL STRUCTURE OF THE D(CG)3 AND N-(2-AMINOETHYL)-1,4-DIAMINOBUTANE COMPLEX


Overview

The DNA fragment d(CG)3 was co-crystallized with N-(2-aminoethyl)-1,4-diaminobutane (PA(24], a chemically synthesized polyamine. The complex crystal contained one polyamine, 3 magnesium cations and one sodium cation per duplex of d(CG)3, and well diffracted the X-ray intensities up to 1.0 A resolution. The d(CG)3 took a left-handed Z-DNA conformation, and the PA(24) molecule electrostatically interacted with the phosphate groups of the d(CG)3 duplex.

About this Structure

292D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Interaction between the left-handed Z-DNA and polyamine. The crystal structure of the d(CG)3 and N-(2-aminoethyl)-1,4-diamino-butane complex., Ohishi H, Kunisawa S, van der Marel G, van Boom JH, Rich A, Wang AH, Tomita K, Hakoshima T, FEBS Lett. 1991 Jun 24;284(2):238-44. PMID:2060642

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