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3av5
From Proteopedia
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==Crystal structure of mouse DNA methyltransferase 1 with AdoHcy== | ==Crystal structure of mouse DNA methyltransferase 1 with AdoHcy== | ||
<StructureSection load='3av5' size='340' side='right' caption='[[3av5]], [[Resolution|resolution]] 3.25Å' scene=''> | <StructureSection load='3av5' size='340' side='right' caption='[[3av5]], [[Resolution|resolution]] 3.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3av5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3av5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AV5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AV5 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3av4|3av4]], [[3av6|3av6]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3av4|3av4]], [[3av6|3av6]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Dnmt1, Dnmt, Met1, Uim ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Dnmt1, Dnmt, Met1, Uim ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> |
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_(cytosine-5-)-methyltransferase DNA (cytosine-5-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.37 2.1.1.37] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_(cytosine-5-)-methyltransferase DNA (cytosine-5-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.37 2.1.1.37] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3av5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3av5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3av5 RCSB], [http://www.ebi.ac.uk/pdbsum/3av5 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3av5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3av5 OCA], [http://pdbe.org/3av5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3av5 RCSB], [http://www.ebi.ac.uk/pdbsum/3av5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3av5 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Lk3 transgenic mice]] |
[[Category: Nakagawa, A]] | [[Category: Nakagawa, A]] | ||
[[Category: Narita, H]] | [[Category: Narita, H]] | ||
Revision as of 05:58, 5 August 2016
Crystal structure of mouse DNA methyltransferase 1 with AdoHcy
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Categories: Lk3 transgenic mice | Nakagawa, A | Narita, H | Suetake, I | Suga, M | Tajima, S | Takeshita, K | Yamashita, E | Cxxc-type zinc finger/c5-methyltransferase family | Dna binding | Hemi-methylation | Methylates cpg residue | Nucleus | Preferentially methylates hemimethylated dna | Transferase
