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3lp6
From Proteopedia
(Difference between revisions)
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==Crystal Structure of Rv3275c-E60A from Mycobacterium tuberculosis at 1.7A resolution== | ==Crystal Structure of Rv3275c-E60A from Mycobacterium tuberculosis at 1.7A resolution== | ||
<StructureSection load='3lp6' size='340' side='right' caption='[[3lp6]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='3lp6' size='340' side='right' caption='[[3lp6]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3lp6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3lp6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LP6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LP6 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MT3375, MTCY71.15c, purE, Rv3275c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MT3375, MTCY71.15c, purE, Rv3275c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr> |
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoribosylaminoimidazole_carboxylase Phosphoribosylaminoimidazole carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.21 4.1.1.21] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoribosylaminoimidazole_carboxylase Phosphoribosylaminoimidazole carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.21 4.1.1.21] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lp6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lp6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lp6 RCSB], [http://www.ebi.ac.uk/pdbsum/3lp6 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lp6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lp6 OCA], [http://pdbe.org/3lp6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lp6 RCSB], [http://www.ebi.ac.uk/pdbsum/3lp6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lp6 ProSAT]</span></td></tr> |
</table> | </table> | ||
| - | == Function == | ||
| - | [[http://www.uniprot.org/uniprot/PURE_MYCTU PURE_MYCTU]] Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lp6 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Phosphoribosylaminoimidazole carboxylase]] | [[Category: Phosphoribosylaminoimidazole carboxylase]] | ||
[[Category: Hung, L W]] | [[Category: Hung, L W]] | ||
Revision as of 07:52, 5 August 2016
Crystal Structure of Rv3275c-E60A from Mycobacterium tuberculosis at 1.7A resolution
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Categories: Phosphoribosylaminoimidazole carboxylase | Hung, L W | ISFI, Integrated Center for Structure and Function Innovation | Kim, C Y | Kim, H | Structural genomic | Terwilliger, T C | Yu, M | Alpha and beta protein | Decarboxylase | Integrated center for structure and function innovation | Isfi | Lyase | PSI, Protein structure initiative | Purine biosynthesis | Tbsgc
