2ao7
From Proteopedia
(Difference between revisions)
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|PDB= 2ao7 |SIZE=350|CAPTION= <scene name='initialview01'>2ao7</scene>, resolution 2.9Å | |PDB= 2ao7 |SIZE=350|CAPTION= <scene name='initialview01'>2ao7</scene>, resolution 2.9Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene> | + | |LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/ADAM10_endopeptidase ADAM10 endopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.81 3.4.24.81] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/ADAM10_endopeptidase ADAM10 endopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.81 3.4.24.81] </span> |
|GENE= ADAM10, MADM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 Bos taurus]) | |GENE= ADAM10, MADM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 Bos taurus]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ao7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ao7 OCA], [http://www.ebi.ac.uk/pdbsum/2ao7 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ao7 RCSB]</span> | ||
}} | }} | ||
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[[Category: Saha, N.]] | [[Category: Saha, N.]] | ||
[[Category: Wimmer-Kleikamp, S H.]] | [[Category: Wimmer-Kleikamp, S H.]] | ||
| - | [[Category: SO4]] | ||
[[Category: disintegrin]] | [[Category: disintegrin]] | ||
[[Category: extracellular]] | [[Category: extracellular]] | ||
[[Category: protease]] | [[Category: protease]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:55:13 2008'' |
Revision as of 22:55, 30 March 2008
| |||||||
| , resolution 2.9Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Gene: | ADAM10, MADM (Bos taurus) | ||||||
| Activity: | ADAM10 endopeptidase, with EC number 3.4.24.81 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Adam10 Disintegrin and cysteine- rich domain
Overview
Ephrin ligands presented on one cell surface associate with their receptors on the surface of a juxtaposed cell, often resulting in cell-cell repulsion. In this issue of Cell, Janes et al. (2005) show that the ephrin ligand can be proteolytically released from its membrane tether by a complex on the opposing cell composed of the ephrin receptor and an ADAM metalloprotease.
About this Structure
2AO7 is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
ADAM and Eph: how Ephrin-signaling cells become detached., Mancia F, Shapiro L, Cell. 2005 Oct 21;123(2):185-7. PMID:16239135
Page seeded by OCA on Mon Mar 31 01:55:13 2008
