2aoz
From Proteopedia
| Line 4: | Line 4: | ||
|PDB= 2aoz |SIZE=350|CAPTION= <scene name='initialview01'>2aoz</scene>, resolution 2.08Å | |PDB= 2aoz |SIZE=350|CAPTION= <scene name='initialview01'>2aoz</scene>, resolution 2.08Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene> | + | |LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aoz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aoz OCA], [http://www.ebi.ac.uk/pdbsum/2aoz PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2aoz RCSB]</span> | ||
}} | }} | ||
| Line 27: | Line 30: | ||
[[Category: Melo, C C.]] | [[Category: Melo, C C.]] | ||
[[Category: Murakami, M T.]] | [[Category: Murakami, M T.]] | ||
| - | [[Category: SO4]] | ||
[[Category: atropoides nummifer]] | [[Category: atropoides nummifer]] | ||
[[Category: myotoxicity]] | [[Category: myotoxicity]] | ||
| Line 33: | Line 35: | ||
[[Category: x-ray diffration]] | [[Category: x-ray diffration]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:55:26 2008'' |
Revision as of 22:55, 30 March 2008
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| , resolution 2.08Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of the myotoxin-II from Atropoides nummifer venom
Overview
Lys49 snake-venom phospholipase A2 (PLA2) homologues are highly myotoxic proteins which, although lacking catalytic activity, possess the ability to disrupt biological membranes, inducing significant muscle-tissue loss and permanent disability in severely envenomed patients. Since the structural basis for their toxic activity is still only partially understood, the structure of myotoxin II, a monomeric Lys49 PLA2 homologue from Atropoides nummifer, has been determined at 2.08 angstroms resolution and the anion-binding site has been characterized.
About this Structure
2AOZ is a Single protein structure of sequence from Atropoides nummifer. Full crystallographic information is available from OCA.
Reference
Structure of myotoxin II, a catalytically inactive Lys49 phospholipase A2 homologue from Atropoides nummifer venom., Murakami MT, Melo CC, Angulo Y, Lomonte B, Arni RK, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 May 1;62(Pt, 5):423-6. Epub 2006 Apr 12. PMID:16682766
Page seeded by OCA on Mon Mar 31 01:55:26 2008
