4v60
From Proteopedia
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<StructureSection load='4v60' size='340' side='right' caption='[[4v60]], [[Resolution|resolution]] 3.50Å' scene=''> | <StructureSection load='4v60' size='340' side='right' caption='[[4v60]], [[Resolution|resolution]] 3.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4v60]] is a 39 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. This structure supersedes the now removed PDB entries | + | <table><tr><td colspan='2'>[[4v60]] is a 39 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. This structure supersedes and combines the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2zuo 2zuo], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2zv4 2zv4] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2zv5 2zv5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V60 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4V60 FirstGlance]. <br> |
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2zuo|2zuo]], [[2zv4|2zv4]], [[2zv5|2zv5]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2zuo|2zuo]], [[2zv4|2zv4]], [[2zv5|2zv5]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4v60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v60 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4v60 RCSB], [http://www.ebi.ac.uk/pdbsum/4v60 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4v60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v60 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4v60 RCSB], [http://www.ebi.ac.uk/pdbsum/4v60 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | {{Large structure}} | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/MVP_RAT MVP_RAT]] Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases (By similarity). | [[http://www.uniprot.org/uniprot/MVP_RAT MVP_RAT]] Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases (By similarity). | ||
Revision as of 13:26, 1 September 2015
The structure of rat liver vault at 3.5 angstrom resolution
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