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3rxw
From Proteopedia
(Difference between revisions)
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==KPC-2 carbapenemase in complex with PSR3-226== | ==KPC-2 carbapenemase in complex with PSR3-226== | ||
<StructureSection load='3rxw' size='340' side='right' caption='[[3rxw]], [[Resolution|resolution]] 1.26Å' scene=''> | <StructureSection load='3rxw' size='340' side='right' caption='[[3rxw]], [[Resolution|resolution]] 1.26Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3rxw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3rxw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. The July 2015 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''New Delhi Metallo-b-Lactamase'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2015_7 10.2210/rcsb_pdb/mom_2015_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RXW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RXW FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=SR3:(2S,3R)-4-(2-AMINO-2-OXOETHOXY)-3-(DIHYDROXY-LAMBDA~4~-SULFANYL)-3-METHYL-4-OXO-2-{[(1E)-3-OXOPROP-1-EN-1-YL]AMINO}BUTANOIC+ACID'>SR3</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=SR3:(2S,3R)-4-(2-AMINO-2-OXOETHOXY)-3-(DIHYDROXY-LAMBDA~4~-SULFANYL)-3-METHYL-4-OXO-2-{[(1E)-3-OXOPROP-1-EN-1-YL]AMINO}BUTANOIC+ACID'>SR3</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rxx|3rxx]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rxx|3rxx]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bla, BLAKPC-2, kpc, kpc1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bla, BLAKPC-2, kpc, kpc1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 "Bacillus pneumoniae" (Schroeter 1886) Flugge 1886])</td></tr> |
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rxw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rxw RCSB], [http://www.ebi.ac.uk/pdbsum/3rxw PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rxw OCA], [http://pdbe.org/3rxw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3rxw RCSB], [http://www.ebi.ac.uk/pdbsum/3rxw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3rxw ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 3rxw" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Beta-lactamase]] | [[Category: Beta-lactamase]] | ||
| - | [[Category: | + | [[Category: New Delhi Metallo-b-Lactamase]] |
| + | [[Category: RCSB PDB Molecule of the Month]] | ||
[[Category: Akker, F van den]] | [[Category: Akker, F van den]] | ||
[[Category: Ke, W]] | [[Category: Ke, W]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
Revision as of 15:28, 5 August 2016
KPC-2 carbapenemase in complex with PSR3-226
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