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2bel
From Proteopedia
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|PDB= 2bel |SIZE=350|CAPTION= <scene name='initialview01'>2bel</scene>, resolution 2.11Å | |PDB= 2bel |SIZE=350|CAPTION= <scene name='initialview01'>2bel</scene>, resolution 2.11Å | ||
|SITE= <scene name='pdbsite=AC1:Cl+Binding+Site+For+Chain+C'>AC1</scene> | |SITE= <scene name='pdbsite=AC1:Cl+Binding+Site+For+Chain+C'>AC1</scene> | ||
| - | |LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene> | + | |LIGAND= <scene name='pdbligand=CBO:CARBENOXOLONE'>CBO</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene> |
| - | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/11-beta-hydroxysteroid_dehydrogenase 11-beta-hydroxysteroid dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.146 1.1.1.146] </span> | |
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bel OCA], [http://www.ebi.ac.uk/pdbsum/2bel PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2bel RCSB]</span> | ||
}} | }} | ||
'''STRUCTURE OF HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP AND CARBENOXOLONE''' | '''STRUCTURE OF HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP AND CARBENOXOLONE''' | ||
| - | |||
| - | ==Disease== | ||
| - | Known diseases associated with this structure: Cortisone reductase deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600713 600713]] | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Svensson, S.]] | [[Category: Svensson, S.]] | ||
[[Category: Wu, X.]] | [[Category: Wu, X.]] | ||
| - | [[Category: CBO]] | ||
| - | [[Category: CL]] | ||
| - | [[Category: NAP]] | ||
[[Category: drug target]] | [[Category: drug target]] | ||
[[Category: glucocorticoid activation]] | [[Category: glucocorticoid activation]] | ||
| Line 46: | Line 43: | ||
[[Category: steroid metabolism]] | [[Category: steroid metabolism]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:05:16 2008'' |
Revision as of 23:05, 30 March 2008
| |||||||
| , resolution 2.11Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | |||||||
| Ligands: | , , | ||||||
| Activity: | 11-beta-hydroxysteroid dehydrogenase, with EC number 1.1.1.146 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
STRUCTURE OF HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP AND CARBENOXOLONE
About this Structure
2BEL is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 02:05:16 2008
Categories: 11-beta-hydroxysteroid dehydrogenase | Homo sapiens | Single protein | Abrahmsen, L. | Arrowsmith, C. | Bray, J. | Debreczeni, J E. | Delft, F Von. | Edwards, A. | Elleby, B. | Kavanagh, K. | Oppermann, U. | Sharma, S. | Sundstrom, M. | Svensson, S. | Wu, X. | Drug target | Glucocorticoid activation | Hormone metabolism | Inhibitor | Microsome | Nadp | Oxidoreductase | Short-chain dehydrogenase/reductase | Steroid metabolism
