3hvg
From Proteopedia
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| <StructureSection load='3hvg' size='340' side='right' caption='[[3hvg]], [[Resolution|resolution]] 2.26Å' scene=''> | <StructureSection load='3hvg' size='340' side='right' caption='[[3hvg]], [[Resolution|resolution]] 2.26Å' scene=''> | ||
| == Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3hvg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3hvg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HVG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HVG FirstGlance]. <br> | 
| </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EV0:2-AMINO-6-PROPYLPYRIMIDIN-4(3H)-ONE'>EV0</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EV0:2-AMINO-6-PROPYLPYRIMIDIN-4(3H)-ONE'>EV0</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
| <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hw1|3hw1]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hw1|3hw1]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BACE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606  | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BACE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | 
| <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hvg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hvg RCSB], [http://www.ebi.ac.uk/pdbsum/3hvg PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hvg OCA], [http://pdbe.org/3hvg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hvg RCSB], [http://www.ebi.ac.uk/pdbsum/3hvg PDBsum]</span></td></tr> | 
| </table> | </table> | ||
| == Function == | == Function == | ||
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|     <text>to colour the structure by Evolutionary Conservation</text> |     <text>to colour the structure by Evolutionary Conservation</text> | ||
|   </jmolCheckbox> |   </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hvg ConSurf]. | 
| <div style="clear:both"></div> | <div style="clear:both"></div> | ||
| <div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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| From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| </div> | </div> | ||
| + | <div class="pdbe-citations 3hvg" style="background-color:#fffaf0;"></div> | ||
| ==See Also== | ==See Also== | ||
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| __TOC__ | __TOC__ | ||
| </StructureSection> | </StructureSection> | ||
| - | [[Category:  | + | [[Category: Human]] | 
| [[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
| [[Category: Barker, J]] | [[Category: Barker, J]] | ||
Revision as of 05:53, 9 February 2016
Structure of bace (beta secretase) in Complex with EV0
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Categories: Human | Memapsin 2 | Barker, J | Ebneth, A | Godemann, R | Kramer, J | Madden, J | Smith, M A | Alzheimer's disease | Amyloid precursor protein secretase | Aspartic endopeptidase | Aspartic protease | Aspartyl protease | Base | Beta-secretase | Disulfide bond | Fluorescence polarisation | Fragment-based drug design | Glycoprotein | Hydrolase | Protease | Transmembrane | Zymogen

