2ye7

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==HSP90 INHIBITORS AND DRUGS FROM FRAGMENT AND VIRTUAL SCREENING==
==HSP90 INHIBITORS AND DRUGS FROM FRAGMENT AND VIRTUAL SCREENING==
<StructureSection load='2ye7' size='340' side='right' caption='[[2ye7]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='2ye7' size='340' side='right' caption='[[2ye7]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ye7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YE7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YE7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ye7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YE7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YE7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2GA:2-[(3,5-DIMETHYL-1H-PYRAZOL-4-YL)SULFANYL]-5-METHYLSULFANYL-1,3,4-THIADIAZOLE'>2GA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2GA:2-[(3,5-DIMETHYL-1H-PYRAZOL-4-YL)SULFANYL]-5-METHYLSULFANYL-1,3,4-THIADIAZOLE'>2GA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bsm|2bsm]], [[1osf|1osf]], [[2wi3|2wi3]], [[2bz5|2bz5]], [[2ccs|2ccs]], [[2yei|2yei]], [[2yeg|2yeg]], [[1yc3|1yc3]], [[1uyf|1uyf]], [[1uyi|1uyi]], [[2ye3|2ye3]], [[2byi|2byi]], [[2vci|2vci]], [[2wi1|2wi1]], [[2xjx|2xjx]], [[2xdk|2xdk]], [[2fwz|2fwz]], [[2xjg|2xjg]], [[1uyh|1uyh]], [[2fwy|2fwy]], [[1uyl|1uyl]], [[1uye|1uye]], [[2xab|2xab]], [[2yeh|2yeh]], [[2xhr|2xhr]], [[1uy7|1uy7]], [[2xht|2xht]], [[2byh|2byh]], [[2wi5|2wi5]], [[2cdd|2cdd]], [[1uy9|1uy9]], [[1yes|1yes]], [[1byq|1byq]], [[1uy8|1uy8]], [[2wi4|2wi4]], [[2bug|2bug]], [[2uwd|2uwd]], [[2xhx|2xhx]], [[2wi7|2wi7]], [[2bt0|2bt0]], [[2yej|2yej]], [[1yer|1yer]], [[2yec|2yec]], [[2xdu|2xdu]], [[1uyg|1uyg]], [[2ccu|2ccu]], [[2xds|2xds]], [[2xdx|2xdx]], [[2xk2|2xk2]], [[2xjj|2xjj]], [[1uyd|1uyd]], [[2wi2|2wi2]], [[2xdl|2xdl]], [[1uy6|1uy6]], [[2yee|2yee]], [[2ye2|2ye2]], [[2vcj|2vcj]], [[1yc4|1yc4]], [[2c2l|2c2l]], [[1uyk|1uyk]], [[2cct|2cct]], [[2wi6|2wi6]], [[1yc1|1yc1]], [[2yed|2yed]], [[1uyc|1uyc]], [[1yet|1yet]], [[2jjc|2jjc]], [[2ye9|2ye9]], [[2yeb|2yeb]], [[2ye4|2ye4]], [[2ye5|2ye5]], [[2yea|2yea]], [[2ye6|2ye6]], [[2yef|2yef]], [[2ye8|2ye8]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bsm|2bsm]], [[1osf|1osf]], [[2wi3|2wi3]], [[2bz5|2bz5]], [[2ccs|2ccs]], [[2yei|2yei]], [[2yeg|2yeg]], [[1yc3|1yc3]], [[1uyf|1uyf]], [[1uyi|1uyi]], [[2ye3|2ye3]], [[2byi|2byi]], [[2vci|2vci]], [[2wi1|2wi1]], [[2xjx|2xjx]], [[2xdk|2xdk]], [[2fwz|2fwz]], [[2xjg|2xjg]], [[1uyh|1uyh]], [[2fwy|2fwy]], [[1uyl|1uyl]], [[1uye|1uye]], [[2xab|2xab]], [[2yeh|2yeh]], [[2xhr|2xhr]], [[1uy7|1uy7]], [[2xht|2xht]], [[2byh|2byh]], [[2wi5|2wi5]], [[2cdd|2cdd]], [[1uy9|1uy9]], [[1yes|1yes]], [[1byq|1byq]], [[1uy8|1uy8]], [[2wi4|2wi4]], [[2bug|2bug]], [[2uwd|2uwd]], [[2xhx|2xhx]], [[2wi7|2wi7]], [[2bt0|2bt0]], [[2yej|2yej]], [[1yer|1yer]], [[2yec|2yec]], [[2xdu|2xdu]], [[1uyg|1uyg]], [[2ccu|2ccu]], [[2xds|2xds]], [[2xdx|2xdx]], [[2xk2|2xk2]], [[2xjj|2xjj]], [[1uyd|1uyd]], [[2wi2|2wi2]], [[2xdl|2xdl]], [[1uy6|1uy6]], [[2yee|2yee]], [[2ye2|2ye2]], [[2vcj|2vcj]], [[1yc4|1yc4]], [[2c2l|2c2l]], [[1uyk|1uyk]], [[2cct|2cct]], [[2wi6|2wi6]], [[1yc1|1yc1]], [[2yed|2yed]], [[1uyc|1uyc]], [[1yet|1yet]], [[2jjc|2jjc]], [[2ye9|2ye9]], [[2yeb|2yeb]], [[2ye4|2ye4]], [[2ye5|2ye5]], [[2yea|2yea]], [[2ye6|2ye6]], [[2yef|2yef]], [[2ye8|2ye8]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ye7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ye7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ye7 RCSB], [http://www.ebi.ac.uk/pdbsum/2ye7 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ye7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ye7 OCA], [http://pdbe.org/2ye7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ye7 RCSB], [http://www.ebi.ac.uk/pdbsum/2ye7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ye7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Baker, L M]]
[[Category: Baker, L M]]
[[Category: Hubbard, R E]]
[[Category: Hubbard, R E]]

Revision as of 10:38, 4 August 2016

HSP90 INHIBITORS AND DRUGS FROM FRAGMENT AND VIRTUAL SCREENING

2ye7, resolution 2.20Å

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