4gca
From Proteopedia
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==Complex of Aldose Reductase with inhibitor IDD 1219== | ==Complex of Aldose Reductase with inhibitor IDD 1219== | ||
<StructureSection load='4gca' size='340' side='right' caption='[[4gca]], [[Resolution|resolution]] 0.90Å' scene=''> | <StructureSection load='4gca' size='340' side='right' caption='[[4gca]], [[Resolution|resolution]] 0.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4gca]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4gca]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GCA FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2X9:{2,6-DIMETHYL-5-[(4,5,7-TRIFLUORO-1,3-BENZOTHIAZOL-2-YL)METHYL]PYRIDIN-3-YL}ACETIC+ACID'>2X9</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2X9:{2,6-DIMETHYL-5-[(4,5,7-TRIFLUORO-1,3-BENZOTHIAZOL-2-YL)METHYL]PYRIDIN-3-YL}ACETIC+ACID'>2X9</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1us0|1us0]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1us0|1us0]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AKR1B1, ALDR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AKR1B1, ALDR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gca FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gca OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gca RCSB], [http://www.ebi.ac.uk/pdbsum/4gca PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gca FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gca OCA], [http://pdbe.org/4gca PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gca RCSB], [http://www.ebi.ac.uk/pdbsum/4gca PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gca ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Aldehyde reductase]] | [[Category: Aldehyde reductase]] | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Geraci, L S]] | [[Category: Geraci, L S]] | ||
[[Category: Podjarny, A D]] | [[Category: Podjarny, A D]] | ||
Revision as of 15:38, 4 August 2016
Complex of Aldose Reductase with inhibitor IDD 1219
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