4p9j
From Proteopedia
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==Crystal Structure of rabbit Ryanodine Receptor 1 SPRY2 Domain (1070-1246)== | ==Crystal Structure of rabbit Ryanodine Receptor 1 SPRY2 Domain (1070-1246)== | ||
<StructureSection load='4p9j' size='340' side='right' caption='[[4p9j]], [[Resolution|resolution]] 1.84Å' scene=''> | <StructureSection load='4p9j' size='340' side='right' caption='[[4p9j]], [[Resolution|resolution]] 1.84Å' scene=''> | ||
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<table><tr><td colspan='2'>[[4p9j]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P9J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P9J FirstGlance]. <br> | <table><tr><td colspan='2'>[[4p9j]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P9J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P9J FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4p9i|4p9i]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4p9i|4p9i]]</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p9j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p9j RCSB], [http://www.ebi.ac.uk/pdbsum/4p9j PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p9j OCA], [http://pdbe.org/4p9j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4p9j RCSB], [http://www.ebi.ac.uk/pdbsum/4p9j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4p9j ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/RYR1_RABIT RYR1_RABIT]] Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high-level exercise increases the open probability of the channel and leads to Ca(2+) leaking into the cytoplasm. Can also mediate the release of Ca(2+) from intracellular stores in neurons, and may thereby promote prolonged Ca(2+) signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis (By similarity).<ref>PMID:10388749</ref> <ref>PMID:22036948</ref> | [[http://www.uniprot.org/uniprot/RYR1_RABIT RYR1_RABIT]] Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high-level exercise increases the open probability of the channel and leads to Ca(2+) leaking into the cytoplasm. Can also mediate the release of Ca(2+) from intracellular stores in neurons, and may thereby promote prolonged Ca(2+) signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis (By similarity).<ref>PMID:10388749</ref> <ref>PMID:22036948</ref> | ||
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| + | ==See Also== | ||
| + | *[[Ryanodine receptor|Ryanodine receptor]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 15:43, 4 August 2016
Crystal Structure of rabbit Ryanodine Receptor 1 SPRY2 Domain (1070-1246)
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