4m7l
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==Crystal structure of the complex between human tissue factor extracellular domain and antibody 10H10 FAB fragment== | ==Crystal structure of the complex between human tissue factor extracellular domain and antibody 10H10 FAB fragment== | ||
<StructureSection load='4m7l' size='340' side='right' caption='[[4m7l]], [[Resolution|resolution]] 3.40Å' scene=''> | <StructureSection load='4m7l' size='340' side='right' caption='[[4m7l]], [[Resolution|resolution]] 3.40Å' scene=''> | ||
| Line 4: | Line 5: | ||
<table><tr><td colspan='2'>[[4m7l]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M7L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M7L FirstGlance]. <br> | <table><tr><td colspan='2'>[[4m7l]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M7L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M7L FirstGlance]. <br> | ||
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr> | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m7l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m7l RCSB], [http://www.ebi.ac.uk/pdbsum/4m7l PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m7l OCA], [http://pdbe.org/4m7l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4m7l RCSB], [http://www.ebi.ac.uk/pdbsum/4m7l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4m7l ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/TF_HUMAN TF_HUMAN]] Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.<ref>PMID:12652293</ref> | [[http://www.uniprot.org/uniprot/TF_HUMAN TF_HUMAN]] Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.<ref>PMID:12652293</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Tissue factor|Tissue factor]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 17:00, 4 August 2016
Crystal structure of the complex between human tissue factor extracellular domain and antibody 10H10 FAB fragment
| |||||||||||
