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3uol

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==Aurora A in complex with SO2-162==
==Aurora A in complex with SO2-162==
<StructureSection load='3uol' size='340' side='right' caption='[[3uol]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='3uol' size='340' side='right' caption='[[3uol]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3uol]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UOL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UOL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3uol]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UOL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UOL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0C7:N~4~-(2-CHLOROPHENYL)-N~2~-[4-(1H-TETRAZOL-5-YL)PHENYL]PYRIMIDINE-2,4-DIAMINE'>0C7</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0C7:N~4~-(2-CHLOROPHENYL)-N~2~-[4-(1H-TETRAZOL-5-YL)PHENYL]PYRIMIDINE-2,4-DIAMINE'>0C7</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3unj|3unj]], [[3unk|3unk]], [[3unz|3unz]], [[3uo4|3uo4]], [[3uo5|3uo5]], [[3uo6|3uo6]], [[3uod|3uod]], [[3uoh|3uoh]], [[3uoj|3uoj]], [[3uok|3uok]], [[3up2|3up2]], [[3up7|3up7]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3unj|3unj]], [[3unk|3unk]], [[3unz|3unz]], [[3uo4|3uo4]], [[3uo5|3uo5]], [[3uo6|3uo6]], [[3uod|3uod]], [[3uoh|3uoh]], [[3uoj|3uoj]], [[3uok|3uok]], [[3up2|3up2]], [[3up7|3up7]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AURKA, AIK, AIRK1, ARK1, AURA, AYK1, BTAK, IAK1, STK15, STK6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AURKA, AIK, AIRK1, ARK1, AURA, AYK1, BTAK, IAK1, STK15, STK6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uol FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uol OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3uol RCSB], [http://www.ebi.ac.uk/pdbsum/3uol PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uol FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uol OCA], [http://pdbe.org/3uol PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3uol RCSB], [http://www.ebi.ac.uk/pdbsum/3uol PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3uol ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3uol" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Martin, M P]]
[[Category: Martin, M P]]

Revision as of 17:56, 4 August 2016

Aurora A in complex with SO2-162

3uol, resolution 2.40Å

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