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3hy7
From Proteopedia
(Difference between revisions)
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<StructureSection load='3hy7' size='340' side='right' caption='[[3hy7]], [[Resolution|resolution]] 1.69Å' scene=''> | <StructureSection load='3hy7' size='340' side='right' caption='[[3hy7]], [[Resolution|resolution]] 1.69Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3hy7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3hy7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HY7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HY7 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=097:(2S,3R)-N~4~-[(1S)-2,2-DIMETHYL-1-(METHYLCARBAMOYL)PROPYL]-N~1~,2-DIHYDROXY-3-(2-METHYLPROPYL)BUTANEDIAMIDE'>097</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=097:(2S,3R)-N~4~-[(1S)-2,2-DIMETHYL-1-(METHYLCARBAMOYL)PROPYL]-N~1~,2-DIHYDROXY-3-(2-METHYLPROPYL)BUTANEDIAMIDE'>097</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3b8z|3b8z]], [[3hy9|3hy9]], [[3hyg|3hyg]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3b8z|3b8z]], [[3hy9|3hy9]], [[3hyg|3hyg]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADAMTS-5, ADAMTS11, ADAMTS5, ADMP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADAMTS-5, ADAMTS11, ADAMTS5, ADMP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hy7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hy7 RCSB], [http://www.ebi.ac.uk/pdbsum/3hy7 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hy7 OCA], [http://pdbe.org/3hy7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hy7 RCSB], [http://www.ebi.ac.uk/pdbsum/3hy7 PDBsum]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hy7 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 3hy7" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Caspers, N]] | [[Category: Caspers, N]] | ||
[[Category: Mathis, K J]] | [[Category: Mathis, K J]] | ||
Revision as of 04:59, 10 February 2016
Crystal Structure of the Catalytic Domain of ADAMTS-5 in Complex with Marimastat
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Categories: Human | Caspers, N | Mathis, K J | Shieh, H S | Tomasselli, A | Tortorella, M D | Williams, J M | Alpha/beta structure | Central five stranded beta-sheet | Cleavage on pair of basic residue | Disulfide bond | Extracellular matrix | Glycoprotein | Hydrolase | Metal-binding | Metalloprotease | Protease | Secreted | Zymogen
