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3u1y
From Proteopedia
(Difference between revisions)
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==Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections== | ==Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections== | ||
<StructureSection load='3u1y' size='340' side='right' caption='[[3u1y]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='3u1y' size='340' side='right' caption='[[3u1y]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3u1y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3u1y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U1Y FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=03I:(2R)-N-HYDROXY-2-METHYL-2-(METHYLSULFONYL)-4-{4-[3-(MORPHOLIN-4-YL)PROPOXY]BIPHENYL-4-YL}BUTANAMIDE'>03I</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=03I:(2R)-N-HYDROXY-2-METHYL-2-(METHYLSULFONYL)-4-{4-[3-(MORPHOLIN-4-YL)PROPOXY]BIPHENYL-4-YL}BUTANAMIDE'>03I</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lpxC, envA, PA4406 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lpxC, envA, PA4406 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u1y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u1y RCSB], [http://www.ebi.ac.uk/pdbsum/3u1y PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u1y OCA], [http://pdbe.org/3u1y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3u1y RCSB], [http://www.ebi.ac.uk/pdbsum/3u1y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3u1y ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 3u1y" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Pseudomonas aeruginosa]] | ||
[[Category: Abramite, J]] | [[Category: Abramite, J]] | ||
[[Category: Brown, M]] | [[Category: Brown, M]] | ||
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[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: Lpxc]] | [[Category: Lpxc]] | ||
| + | [[Category: Pseudomonas aeruginosa]] | ||
Revision as of 18:37, 4 August 2016
Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections
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