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2xfj
From Proteopedia
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==HUMAN BACE-1 IN COMPLEX WITH N-((1S,2R)-3-(((1S)-2-(CYCLOHEXYLAMINO)-1-METHYL-2-OXOETHYL)AMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL)-3-(ETHYLAMINO)-5-(2-OXO-1-PYRROLIDINYL)BENZAMIDE== | ==HUMAN BACE-1 IN COMPLEX WITH N-((1S,2R)-3-(((1S)-2-(CYCLOHEXYLAMINO)-1-METHYL-2-OXOETHYL)AMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL)-3-(ETHYLAMINO)-5-(2-OXO-1-PYRROLIDINYL)BENZAMIDE== | ||
<StructureSection load='2xfj' size='340' side='right' caption='[[2xfj]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='2xfj' size='340' side='right' caption='[[2xfj]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2xfj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2xfj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XFJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XFJ FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=VG5:N-[(1S,2R)-1-BENZYL-3-{[(1S)-2-(CYCLOHEXYLAMINO)-1-METHYL-2-OXOETHYL]AMINO}-2-HYDROXYPROPYL]-3-(ETHYLAMINO)-5-(2-OXOPYRROLIDIN-1-YL)BENZAMIDE'>VG5</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=VG5:N-[(1S,2R)-1-BENZYL-3-{[(1S)-2-(CYCLOHEXYLAMINO)-1-METHYL-2-OXOETHYL]AMINO}-2-HYDROXYPROPYL]-3-(ETHYLAMINO)-5-(2-OXOPYRROLIDIN-1-YL)BENZAMIDE'>VG5</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xn3|1xn3]], [[2wf3|2wf3]], [[2wf1|2wf1]], [[2vnm|2vnm]], [[2wf4|2wf4]], [[2fdp|2fdp]], [[2vj6|2vj6]], [[2wf2|2wf2]], [[1ym4|1ym4]], [[1sgz|1sgz]], [[1ujk|1ujk]], [[2va7|2va7]], [[2wjo|2wjo]], [[2wez|2wez]], [[1ym2|1ym2]], [[1py1|1py1]], [[1w50|1w50]], [[2vj7|2vj7]], [[2wf0|2wf0]], [[1w51|1w51]], [[1tqf|1tqf]], [[1m4h|1m4h]], [[1xn2|1xn2]], [[2viy|2viy]], [[2va6|2va6]], [[2vie|2vie]], [[2viz|2viz]], [[2b8l|2b8l]], [[2va5|2va5]], [[2b8v|2b8v]], [[1fkn|1fkn]], [[1xs7|1xs7]], [[2vij|2vij]], [[2vkm|2vkm]], [[2vj9|2vj9]], [[2vnn|2vnn]], [[1ujj|1ujj]], [[2xfi|2xfi]], [[2xfk|2xfk]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xn3|1xn3]], [[2wf3|2wf3]], [[2wf1|2wf1]], [[2vnm|2vnm]], [[2wf4|2wf4]], [[2fdp|2fdp]], [[2vj6|2vj6]], [[2wf2|2wf2]], [[1ym4|1ym4]], [[1sgz|1sgz]], [[1ujk|1ujk]], [[2va7|2va7]], [[2wjo|2wjo]], [[2wez|2wez]], [[1ym2|1ym2]], [[1py1|1py1]], [[1w50|1w50]], [[2vj7|2vj7]], [[2wf0|2wf0]], [[1w51|1w51]], [[1tqf|1tqf]], [[1m4h|1m4h]], [[1xn2|1xn2]], [[2viy|2viy]], [[2va6|2va6]], [[2vie|2vie]], [[2viz|2viz]], [[2b8l|2b8l]], [[2va5|2va5]], [[2b8v|2b8v]], [[1fkn|1fkn]], [[1xs7|1xs7]], [[2vij|2vij]], [[2vkm|2vkm]], [[2vj9|2vj9]], [[2vnn|2vnn]], [[1ujj|1ujj]], [[2xfi|2xfi]], [[2xfk|2xfk]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xfj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xfj RCSB], [http://www.ebi.ac.uk/pdbsum/2xfj PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xfj OCA], [http://pdbe.org/2xfj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xfj RCSB], [http://www.ebi.ac.uk/pdbsum/2xfj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xfj ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2xfj ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2xfj" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
[[Category: Brien, A O]] | [[Category: Brien, A O]] | ||
Revision as of 19:55, 4 August 2016
HUMAN BACE-1 IN COMPLEX WITH N-((1S,2R)-3-(((1S)-2-(CYCLOHEXYLAMINO)-1-METHYL-2-OXOETHYL)AMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL)-3-(ETHYLAMINO)-5-(2-OXO-1-PYRROLIDINYL)BENZAMIDE
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Categories: Human | Memapsin 2 | Brien, A O | Clarke, B | Cutler, L | Demont, E | Dingwall, C | Dunsdon, R | Hawkins, J | Howes, C | Hussain, I | Maile, G | Matico, R | Mosley, J | Naylor, A | Redshaw, S | Rowland, P | Smith, K J | Soleil, V | Sweitzer, S | Theobald, P | Vesey, D | Walter, D S | Wayne, G | Hydrolase | Protease | Zymogen
