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4btl
From Proteopedia
(Difference between revisions)
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==Aromatic interactions in acetylcholinesterase-inhibitor complexes== | ==Aromatic interactions in acetylcholinesterase-inhibitor complexes== | ||
<StructureSection load='4btl' size='340' side='right' caption='[[4btl]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='4btl' size='340' side='right' caption='[[4btl]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4btl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4btl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BTL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BTL FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GZ:4-(2-CHLORO-6-NITROPHENOXY)-N-[2-(DIETHYLAMINO)ETHYL]BENZENESULFONAMIDE'>5GZ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PE3:3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL'>PE3</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GZ:4-(2-CHLORO-6-NITROPHENOXY)-N-[2-(DIETHYLAMINO)ETHYL]BENZENESULFONAMIDE'>5GZ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PE3:3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL'>PE3</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4btl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4btl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4btl RCSB], [http://www.ebi.ac.uk/pdbsum/4btl PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4btl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4btl OCA], [http://pdbe.org/4btl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4btl RCSB], [http://www.ebi.ac.uk/pdbsum/4btl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4btl ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4btl" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
*[[Acetylcholinesterase|Acetylcholinesterase]] | *[[Acetylcholinesterase|Acetylcholinesterase]] | ||
| + | *[[3D structures of acetylcholinesterase|3D structures of acetylcholinesterase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Acetylcholinesterase]] | [[Category: Acetylcholinesterase]] | ||
| - | [[Category: | + | [[Category: Lk3 transgenic mice]] |
[[Category: Akfur, C]] | [[Category: Akfur, C]] | ||
[[Category: Allgardsson, A]] | [[Category: Allgardsson, A]] | ||
Revision as of 21:05, 4 August 2016
Aromatic interactions in acetylcholinesterase-inhibitor complexes
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