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3ixt
From Proteopedia
(Difference between revisions)
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==Crystal Structure of Motavizumab Fab Bound to Peptide Epitope== | ==Crystal Structure of Motavizumab Fab Bound to Peptide Epitope== | ||
<StructureSection load='3ixt' size='340' side='right' caption='[[3ixt]], [[Resolution|resolution]] 2.75Å' scene=''> | <StructureSection load='3ixt' size='340' side='right' caption='[[3ixt]], [[Resolution|resolution]] 2.75Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3ixt]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_respiratory_syncytial_virus Human respiratory syncytial virus] and [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3ixt]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_respiratory_syncytial_virus Human respiratory syncytial virus] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IXT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IXT FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ixt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ixt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ixt RCSB], [http://www.ebi.ac.uk/pdbsum/3ixt PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ixt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ixt OCA], [http://pdbe.org/3ixt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ixt RCSB], [http://www.ebi.ac.uk/pdbsum/3ixt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ixt ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ixt ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 3ixt" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[ | + | *[[3D structures of monoclonal antibody|3D structures of monoclonal antibody]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human respiratory syncytial virus]] | [[Category: Human respiratory syncytial virus]] | ||
| - | [[Category: | + | [[Category: Lk3 transgenic mice]] |
[[Category: Chen, M]] | [[Category: Chen, M]] | ||
[[Category: Graham, B S]] | [[Category: Graham, B S]] | ||
Revision as of 21:27, 4 August 2016
Crystal Structure of Motavizumab Fab Bound to Peptide Epitope
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Categories: Human respiratory syncytial virus | Lk3 transgenic mice | Chen, M | Graham, B S | Kim, A | Kwong, P D | McLellan, J S | Yang, Y | Cell membrane | Cleavage on pair of basic residue | Complex | Disulfide bond | Envelope protein | Fab | Fusion protein | Glycoprotein | Immune system | Lipoprotein | Membrane | Monoclonal | Motavizumab | Palmitate | Rsv | Synagi | Transmembrane | Virion
