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4mwm

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Current revision (15:29, 1 June 2016) (edit) (undo)
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==Triclinic HEWL co-crystallised with cisplatin, studied at a data collection temperature of 200K==
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#REDIRECT [[5hq1]] This PDB entry is obsolete and replaced by 5hq1
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<StructureSection load='4mwm' size='340' side='right' caption='[[4mwm]], [[Resolution|resolution]] 1.12&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4mwm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MWM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MWM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MEB:2-METHYLPROP-1-ENE'>MEB</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PT:PLATINUM+(II)+ION'>PT</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mwk|4mwk]], [[4mwn|4mwn]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mwm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mwm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mwm RCSB], [http://www.ebi.ac.uk/pdbsum/4mwm PDBsum]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Gallus gallus]]
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[[Category: Lysozyme]]
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[[Category: Helliwell, J R]]
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[[Category: Tanley, S W.M]]
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[[Category: Hydrolase]]
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Current revision

  1. REDIRECT 5hq1 This PDB entry is obsolete and replaced by 5hq1

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