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4mr6

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==Crystal Structure of the second bromodomain of human BRD2 in complex with a quinazolinone ligand (RVX-208)==
==Crystal Structure of the second bromodomain of human BRD2 in complex with a quinazolinone ligand (RVX-208)==
<StructureSection load='4mr6' size='340' side='right' caption='[[4mr6]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
<StructureSection load='4mr6' size='340' side='right' caption='[[4mr6]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1K0:2-[4-(2-HYDROXYETHOXY)-3,5-DIMETHYLPHENYL]-5,7-DIMETHOXYQUINAZOLIN-4(3H)-ONE'>1K0</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1K0:2-[4-(2-HYDROXYETHOXY)-3,5-DIMETHYLPHENYL]-5,7-DIMETHOXYQUINAZOLIN-4(3H)-ONE'>1K0</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRD2, KIAA9001, RING3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRD2, KIAA9001, RING3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mr6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mr6 RCSB], [http://www.ebi.ac.uk/pdbsum/4mr6 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mr6 OCA], [http://pdbe.org/4mr6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mr6 RCSB], [http://www.ebi.ac.uk/pdbsum/4mr6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mr6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4mr6" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Bromodomain-containing protein|Bromodomain-containing protein]]
== References ==
== References ==
<references/>
<references/>

Revision as of 03:00, 5 August 2016

Crystal Structure of the second bromodomain of human BRD2 in complex with a quinazolinone ligand (RVX-208)

4mr6, resolution 1.67Å

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