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4gw8
From Proteopedia
(Difference between revisions)
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==Human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and Leucettine L41== | ==Human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and Leucettine L41== | ||
<StructureSection load='4gw8' size='340' side='right' caption='[[4gw8]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='4gw8' size='340' side='right' caption='[[4gw8]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4gw8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4gw8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GW8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GW8 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3RA:5-(1,3-BENZODIOXOL-5-YLMETHYL)-2-(PHENYLAMINO)-4H-IMIDAZOL-4-ONE'>3RA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3RA:5-(1,3-BENZODIOXOL-5-YLMETHYL)-2-(PHENYLAMINO)-4H-IMIDAZOL-4-ONE'>3RA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PIM1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PIM1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gw8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gw8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gw8 RCSB], [http://www.ebi.ac.uk/pdbsum/4gw8 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gw8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gw8 OCA], [http://pdbe.org/4gw8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gw8 RCSB], [http://www.ebi.ac.uk/pdbsum/4gw8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gw8 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4gw8" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
Revision as of 03:10, 5 August 2016
Human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and Leucettine L41
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Categories: Human | Non-specific serine/threonine protein kinase | Arrowsmith, C H | Bountra, C | Bullock, A | Delft, F von | Edwards, A | Filippakopoulos, P | Knapp, S | Meijer, L | Structural genomic | Alternative initiation | Atp-binding | Cell cycle | Cell membrane | Host-virus interaction | Kinase | Manganese | Membrane | Metal-binding | Nucleotide-binding | Nucleus | Oncogene | Phosphoprotein | Pim1 | Proto-oncogene | Serine-threonine | Serine/threonine-protein kinase | Sgc | Transferase | Viral immunoevasion | Virion | Virulence
