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3pwu
From Proteopedia
(Difference between revisions)
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==An immmunodominant CTL epitope from rinderpest virus presented by cattle MHC class I molecule N*01801(BoLA-A11)== | ==An immmunodominant CTL epitope from rinderpest virus presented by cattle MHC class I molecule N*01801(BoLA-A11)== | ||
<StructureSection load='3pwu' size='340' side='right' caption='[[3pwu]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='3pwu' size='340' side='right' caption='[[3pwu]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3pwu]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3pwu]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PWU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PWU FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LA-A11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LA-A11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 BOVIN]), B2m ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pwu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pwu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pwu RCSB], [http://www.ebi.ac.uk/pdbsum/3pwu PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pwu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pwu OCA], [http://pdbe.org/3pwu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3pwu RCSB], [http://www.ebi.ac.uk/pdbsum/3pwu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3pwu ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[http://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | + | [[http://www.uniprot.org/uniprot/Q95477_BOVIN Q95477_BOVIN]] Involved in the presentation of foreign antigens to the immune system.[SAAS:SAAS00004076] [[http://www.uniprot.org/uniprot/HEMA_RINDR HEMA_RINDR]] Attaches the virus to cell receptors and thereby initiating infection. Binding of H protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion (By similarity). Down-regulates human MCP/CD46 cell surface expression.<ref>PMID:9811778</ref> [[http://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 3pwu" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Bovin]] |
| - | [[Category: | + | [[Category: Lk3 transgenic mice]] |
[[Category: Gao, F]] | [[Category: Gao, F]] | ||
[[Category: Gao, G F]] | [[Category: Gao, G F]] | ||
Revision as of 04:21, 5 August 2016
An immmunodominant CTL epitope from rinderpest virus presented by cattle MHC class I molecule N*01801(BoLA-A11)
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Categories: Bovin | Lk3 transgenic mice | Gao, F | Gao, G F | Li, Q | Li, X | Liu, J | Qi, J | Xia, C | Zhang, N | Immune system | Immunodominant epitope cattle | Mhc bola conformation
