2zg1
From Proteopedia
(Difference between revisions)
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==Crystal Structure of Two N-terminal Domains of Siglec-5 in Complex with 6'-Sialyllactose== | ==Crystal Structure of Two N-terminal Domains of Siglec-5 in Complex with 6'-Sialyllactose== | ||
<StructureSection load='2zg1' size='340' side='right' caption='[[2zg1]], [[Resolution|resolution]] 2.70Å' scene=''> | <StructureSection load='2zg1' size='340' side='right' caption='[[2zg1]], [[Resolution|resolution]] 2.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2zg1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2zg1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZG1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZG1 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1o7s|1o7s]], [[1qfo|1qfo]], [[2zg2|2zg2]], [[2zg3|2zg3]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1o7s|1o7s]], [[1qfo|1qfo]], [[2zg2|2zg2]], [[2zg3|2zg3]]</td></tr> | ||
- | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SIGLEC5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SIGLEC5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zg1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zg1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zg1 RCSB], [http://www.ebi.ac.uk/pdbsum/2zg1 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zg1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zg1 OCA], [http://pdbe.org/2zg1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zg1 RCSB], [http://www.ebi.ac.uk/pdbsum/2zg1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zg1 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
- | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zg1 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
+ | <div class="pdbe-citations 2zg1" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Human]] |
[[Category: Sun, P D]] | [[Category: Sun, P D]] | ||
[[Category: Zhuravleva, M A]] | [[Category: Zhuravleva, M A]] |
Revision as of 05:39, 5 August 2016
Crystal Structure of Two N-terminal Domains of Siglec-5 in Complex with 6'-Sialyllactose
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Categories: Human | Sun, P D | Zhuravleva, M A | 6'-sialyllactose complex | C2-set | Cell adhesion | Glycoprotein | Ig-like domain | Immune system-carbohydrate binding protein complex | Immunoglobulin domain | Lectin | Membrane | Sialic acid | Siglec-5 inhibitory receptor | Transmembrane | Two-domain structure | V-set