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3ciu
From Proteopedia
(Difference between revisions)
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==Site-Selective Glycosylation of Cysteine-93 beta on the Surface of Bovine Hemoglobin and its Application as a Novel Oxygen Therapeutic== | ==Site-Selective Glycosylation of Cysteine-93 beta on the Surface of Bovine Hemoglobin and its Application as a Novel Oxygen Therapeutic== | ||
<StructureSection load='3ciu' size='340' side='right' caption='[[3ciu]], [[Resolution|resolution]] 3.50Å' scene=''> | <StructureSection load='3ciu' size='340' side='right' caption='[[3ciu]], [[Resolution|resolution]] 3.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3ciu]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3ciu]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CIU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CIU FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5DP:5-(2,5-DIOXOPYRROLIDIN-1-YL)-N-[2-(2-{2-[(4-O-ALPHA-D-IDOPYRANOSYL-ALPHA-D-MANNOPYRANOSYL)OXY]ETHOXY}ETHOXY)ETHYL]PENTANAMIDE'>5DP</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5DP:5-(2,5-DIOXOPYRROLIDIN-1-YL)-N-[2-(2-{2-[(4-O-ALPHA-D-IDOPYRANOSYL-ALPHA-D-MANNOPYRANOSYL)OXY]ETHOXY}ETHOXY)ETHYL]PENTANAMIDE'>5DP</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HBA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HBA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 BOVIN]), HBB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 BOVIN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ciu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ciu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ciu RCSB], [http://www.ebi.ac.uk/pdbsum/3ciu PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ciu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ciu OCA], [http://pdbe.org/3ciu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ciu RCSB], [http://www.ebi.ac.uk/pdbsum/3ciu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ciu ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ciu ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Bovin]] |
[[Category: Bhatt, V S]] | [[Category: Bhatt, V S]] | ||
[[Category: Palmer, A F]] | [[Category: Palmer, A F]] | ||
Revision as of 07:03, 5 August 2016
Site-Selective Glycosylation of Cysteine-93 beta on the Surface of Bovine Hemoglobin and its Application as a Novel Oxygen Therapeutic
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Categories: Bovin | Bhatt, V S | Palmer, A F | Sun, G | Wang, P G | Zhang, Y | Blood substitute | Glycosylation | Heme | Hemoglobin | Iron | Oxygen binding | Oxygen carrier | Oxygen transport | Site-selective | Transport
