2y3a
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==CRYSTAL STRUCTURE OF P110BETA IN COMPLEX WITH ICSH2 OF P85BETA AND THE DRUG GDC-0941== | ==CRYSTAL STRUCTURE OF P110BETA IN COMPLEX WITH ICSH2 OF P85BETA AND THE DRUG GDC-0941== | ||
<StructureSection load='2y3a' size='340' side='right' caption='[[2y3a]], [[Resolution|resolution]] 3.30Å' scene=''> | <StructureSection load='2y3a' size='340' side='right' caption='[[2y3a]], [[Resolution|resolution]] 3.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2y3a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2y3a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y3A FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GD9:2-(1H-INDAZOL-4-YL)-6-{[4-(METHYLSULFONYL)PIPERAZIN-1-YL]METHYL}-4-MORPHOLIN-4-YL-THIENO[3,2-D]PYRIMIDINE'>GD9</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GD9:2-(1H-INDAZOL-4-YL)-6-{[4-(METHYLSULFONYL)PIPERAZIN-1-YL]METHYL}-4-MORPHOLIN-4-YL-THIENO[3,2-D]PYRIMIDINE'>GD9</scene></td></tr> | ||
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nicotinate_riboside_kinase Nicotinate riboside kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.173 2.7.1.173] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y3a RCSB], [http://www.ebi.ac.uk/pdbsum/2y3a PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3a OCA], [http://pdbe.org/2y3a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y3a RCSB], [http://www.ebi.ac.uk/pdbsum/2y3a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y3a ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| Line 17: | Line 18: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2y3a" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| Line 24: | Line 26: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Lk3 transgenic mice]] |
| - | [[Category: | + | [[Category: Nicotinate riboside kinase]] |
[[Category: Perisic, O]] | [[Category: Perisic, O]] | ||
[[Category: Vadas, O]] | [[Category: Vadas, O]] | ||
| Line 32: | Line 34: | ||
[[Category: Phosphoinositide 3-kinase]] | [[Category: Phosphoinositide 3-kinase]] | ||
[[Category: Rtk]] | [[Category: Rtk]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 08:05, 5 August 2016
CRYSTAL STRUCTURE OF P110BETA IN COMPLEX WITH ICSH2 OF P85BETA AND THE DRUG GDC-0941
| |||||||||||
