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2c5c
From Proteopedia
(Difference between revisions)
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<StructureSection load='2c5c' size='340' side='right' caption='[[2c5c]], [[Resolution|resolution]] 2.94Å' scene=''> | <StructureSection load='2c5c' size='340' side='right' caption='[[2c5c]], [[Resolution|resolution]] 2.94Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2c5c]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2c5c]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Bph30 Bph30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C5C FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=S10:DIETHYL+PROPANE-1,3-DIYLBISCARBAMATE'>S10</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=S10:DIETHYL+PROPANE-1,3-DIYLBISCARBAMATE'>S10</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c5c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c5c RCSB], [http://www.ebi.ac.uk/pdbsum/2c5c PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c5c OCA], [http://pdbe.org/2c5c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c5c RCSB], [http://www.ebi.ac.uk/pdbsum/2c5c PDBsum]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[http://www.uniprot.org/uniprot/ | + | [[http://www.uniprot.org/uniprot/STXB_BPH19 STXB_BPH19]] The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Bph30]] |
[[Category: Dodd, R B]] | [[Category: Dodd, R B]] | ||
[[Category: Read, R J]] | [[Category: Read, R J]] | ||
Revision as of 13:55, 11 September 2015
SHIGA-LIKE TOXIN 1 B SUBUNIT COMPLEXED WITH A BIVALENT INHIBITOR
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