This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4hy6
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ1== | ==Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ1== | ||
<StructureSection load='4hy6' size='340' side='right' caption='[[4hy6]], [[Resolution|resolution]] 1.65Å' scene=''> | <StructureSection load='4hy6' size='340' side='right' caption='[[4hy6]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4hy6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4hy6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HY6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HY6 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FJ1:6,6-DIMETHYL-3-(TRIFLUOROMETHYL)-1,5,6,7-TETRAHYDRO-4H-INDAZOL-4-ONE'>FJ1</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FJ1:6,6-DIMETHYL-3-(TRIFLUOROMETHYL)-1,5,6,7-TETRAHYDRO-4H-INDAZOL-4-ONE'>FJ1</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HSP90AA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HSP90AA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hy6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hy6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hy6 RCSB], [http://www.ebi.ac.uk/pdbsum/4hy6 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hy6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hy6 OCA], [http://pdbe.org/4hy6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hy6 RCSB], [http://www.ebi.ac.uk/pdbsum/4hy6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hy6 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| Line 16: | Line 17: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: He, J H]] | [[Category: He, J H]] | ||
[[Category: Li, J]] | [[Category: Li, J]] | ||
Revision as of 13:14, 5 August 2016
Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ1
| |||||||||||
