4wwn

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==Crystal structure of human PI3K-gamma in complex with (S)-N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine AMG319 inhibitor==
==Crystal structure of human PI3K-gamma in complex with (S)-N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine AMG319 inhibitor==
<StructureSection load='4wwn' size='340' side='right' caption='[[4wwn]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='4wwn' size='340' side='right' caption='[[4wwn]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3VC:N-{(1S)-1-[7-FLUORO-2-(PYRIDIN-2-YL)QUINOLIN-3-YL]ETHYL}-9H-PURIN-6-AMINE'>3VC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3VC:N-{(1S)-1-[7-FLUORO-2-(PYRIDIN-2-YL)QUINOLIN-3-YL]ETHYL}-9H-PURIN-6-AMINE'>3VC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wwo|4wwo]], [[4wwp|4wwp]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wwo|4wwo]], [[4wwp|4wwp]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wwn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wwn RCSB], [http://www.ebi.ac.uk/pdbsum/4wwn PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wwn OCA], [http://pdbe.org/4wwn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wwn RCSB], [http://www.ebi.ac.uk/pdbsum/4wwn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wwn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4wwn" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Phosphoinositide 3-Kinases|Phosphoinositide 3-Kinases]]
== References ==
== References ==
<references/>
<references/>

Revision as of 17:08, 11 August 2016

Crystal structure of human PI3K-gamma in complex with (S)-N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine AMG319 inhibitor

4wwn, resolution 2.70Å

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