3fal

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==humanRXR alpha & mouse LXR alpha complexed with Retenoic acid and GSK2186==
==humanRXR alpha & mouse LXR alpha complexed with Retenoic acid and GSK2186==
<StructureSection load='3fal' size='340' side='right' caption='[[3fal]], [[Resolution|resolution]] 2.36&Aring;' scene=''>
<StructureSection load='3fal' size='340' side='right' caption='[[3fal]], [[Resolution|resolution]] 2.36&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3fal]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FAL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FAL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3fal]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FAL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FAL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LO2:2-{4-[BUTYL(3-CHLORO-4,5-DIMETHOXYBENZYL)AMINO]PHENYL}-1,1,1,3,3,3-HEXAFLUOROPROPAN-2-OL'>LO2</scene>, <scene name='pdbligand=REA:RETINOIC+ACID'>REA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LO2:2-{4-[BUTYL(3-CHLORO-4,5-DIMETHOXYBENZYL)AMINO]PHENYL}-1,1,1,3,3,3-HEXAFLUOROPROPAN-2-OL'>LO2</scene>, <scene name='pdbligand=REA:RETINOIC+ACID'>REA</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RXRA, NR2B1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), Nr1h3, Lxra ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RXRA, NR2B1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), Nr1h3, Lxra ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fal OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fal RCSB], [http://www.ebi.ac.uk/pdbsum/3fal PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fal OCA], [http://pdbe.org/3fal PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fal RCSB], [http://www.ebi.ac.uk/pdbsum/3fal PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3fal ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fal ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3fal" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Human]]
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[[Category: Mus musculus]]
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[[Category: Lk3 transgenic mice]]
[[Category: Billin, A N]]
[[Category: Billin, A N]]
[[Category: Campobasso, N]]
[[Category: Campobasso, N]]

Revision as of 17:51, 5 August 2016

humanRXR alpha & mouse LXR alpha complexed with Retenoic acid and GSK2186

3fal, resolution 2.36Å

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