3ko6
From Proteopedia
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==Crystal structure of yeast free methionine-R-sulfoxide reductase Ykg9 in complex with the substrate== | ==Crystal structure of yeast free methionine-R-sulfoxide reductase Ykg9 in complex with the substrate== | ||
<StructureSection load='3ko6' size='340' side='right' caption='[[3ko6]], [[Resolution|resolution]] 2.55Å' scene=''> | <StructureSection load='3ko6' size='340' side='right' caption='[[3ko6]], [[Resolution|resolution]] 2.55Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3ko6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3ko6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KO6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KO6 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SME:METHIONINE+SULFOXIDE'>SME</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SME:METHIONINE+SULFOXIDE'>SME</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">YKL069W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id= | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">YKL069W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr> |
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-methionine_(R)-S-oxide_reductase L-methionine (R)-S-oxide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.4.14 1.8.4.14] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-methionine_(R)-S-oxide_reductase L-methionine (R)-S-oxide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.4.14 1.8.4.14] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ko6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ko6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ko6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ko6 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ko6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ko6 OCA], [http://pdbe.org/3ko6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ko6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ko6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ko6 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[http://www.uniprot.org/uniprot/ | + | [[http://www.uniprot.org/uniprot/FRMSR_YEAST FRMSR_YEAST]] Catalyzes the reversible oxidation-reduction of the R-enantiomer of free methionine sulfoxide to methionine. Does not act on S-enantiomer of free methionine sulfoxide or R-enantiomer of dabsylated methionine sulfoxide. Involved in protection against oxidative stress.<ref>PMID:19049972</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Baker's yeast]] |
[[Category: Chen, Y]] | [[Category: Chen, Y]] | ||
[[Category: Guo, P C]] | [[Category: Guo, P C]] | ||
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[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Product dissociation]] | [[Category: Product dissociation]] | ||
| + | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Substrate binding]] | [[Category: Substrate binding]] | ||
Revision as of 19:28, 5 August 2016
Crystal structure of yeast free methionine-R-sulfoxide reductase Ykg9 in complex with the substrate
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