2xqa
From Proteopedia
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==PENTAMERIC LIGAND GATED ION CHANNEL GLIC IN COMPLEX WITH TETRABUTYLANTIMONY (TBSB)== | ==PENTAMERIC LIGAND GATED ION CHANNEL GLIC IN COMPLEX WITH TETRABUTYLANTIMONY (TBSB)== | ||
<StructureSection load='2xqa' size='340' side='right' caption='[[2xqa]], [[Resolution|resolution]] 3.70Å' scene=''> | <StructureSection load='2xqa' size='340' side='right' caption='[[2xqa]], [[Resolution|resolution]] 3.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2xqa]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2xqa]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Glovi Glovi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XQA FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SB:ANTIMONY+(III)+ION'>SB</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SB:ANTIMONY+(III)+ION'>SB</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xq7|2xq7]], [[2xq9|2xq9]], [[2xq5|2xq5]], [[2xq3|2xq3]], [[2xq8|2xq8]], [[2xq4|2xq4]], [[2xq6|2xq6]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xq7|2xq7]], [[2xq9|2xq9]], [[2xq5|2xq5]], [[2xq3|2xq3]], [[2xq8|2xq8]], [[2xq4|2xq4]], [[2xq6|2xq6]]</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xqa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xqa RCSB], [http://www.ebi.ac.uk/pdbsum/2xqa PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xqa OCA], [http://pdbe.org/2xqa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xqa RCSB], [http://www.ebi.ac.uk/pdbsum/2xqa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xqa ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[http://www.uniprot.org/uniprot/ | + | [[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2xqa" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Glovi]] |
[[Category: Bertozzi, C]] | [[Category: Bertozzi, C]] | ||
[[Category: Dutzler, R]] | [[Category: Dutzler, R]] | ||
Revision as of 21:13, 5 August 2016
PENTAMERIC LIGAND GATED ION CHANNEL GLIC IN COMPLEX WITH TETRABUTYLANTIMONY (TBSB)
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