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4gv2

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==Human ARTD3 (PARP3) - Catalytic domain in complex with inhibitor ME0354==
==Human ARTD3 (PARP3) - Catalytic domain in complex with inhibitor ME0354==
<StructureSection load='4gv2' size='340' side='right' caption='[[4gv2]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='4gv2' size='340' side='right' caption='[[4gv2]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4gv2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GV2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GV2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4gv2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GV2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GV2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5ME:3-(4-OXO-3,4-DIHYDROQUINAZOLIN-2-YL)-N-[(1R)-1-(PYRIDIN-2-YL)ETHYL]PROPANAMIDE'>5ME</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5ME:3-(4-OXO-3,4-DIHYDROQUINAZOLIN-2-YL)-N-[(1R)-1-(PYRIDIN-2-YL)ETHYL]PROPANAMIDE'>5ME</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4gv0|4gv0]], [[4gv4|4gv4]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4gv0|4gv0]], [[4gv4|4gv4]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PARP3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PARP3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gv2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gv2 RCSB], [http://www.ebi.ac.uk/pdbsum/4gv2 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gv2 OCA], [http://pdbe.org/4gv2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gv2 RCSB], [http://www.ebi.ac.uk/pdbsum/4gv2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gv2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4gv2" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Andersson, C D]]
[[Category: Andersson, C D]]
[[Category: Ekblad, T]]
[[Category: Ekblad, T]]

Revision as of 22:47, 5 August 2016

Human ARTD3 (PARP3) - Catalytic domain in complex with inhibitor ME0354

4gv2, resolution 1.80Å

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