4ds7

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==Crystal structure of yeast calmodulin bound to the C-terminal fragment of spindle pole body protein Spc110==
==Crystal structure of yeast calmodulin bound to the C-terminal fragment of spindle pole body protein Spc110==
<StructureSection load='4ds7' size='340' side='right' caption='[[4ds7]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
<StructureSection load='4ds7' size='340' side='right' caption='[[4ds7]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4ds7]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis] and [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DS7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DS7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4ds7]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast] and [http://en.wikipedia.org/wiki/Candida_sphaerica Candida sphaerica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DS7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DS7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SR:STRONTIUM+ION'>SR</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SR:STRONTIUM+ION'>SR</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lkj|1lkj]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lkj|1lkj]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CMD1, KLLA0B09427g ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28985 Kluyveromyces lactis]), SPC110, NUF1, XCM1, YDR356W, D9476.3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Saccharomyces cerevisiae S288c])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CMD1, KLLA0B09427g ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284590 Candida sphaerica]), SPC110, NUF1, XCM1, YDR356W, D9476.3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ds7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ds7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ds7 RCSB], [http://www.ebi.ac.uk/pdbsum/4ds7 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ds7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ds7 OCA], [http://pdbe.org/4ds7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ds7 RCSB], [http://www.ebi.ac.uk/pdbsum/4ds7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ds7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SP110_YEAST SP110_YEAST]] Component of the spindle pole body (SPB) required for the proper execution of spindle pole body (SPB) duplication. Potential role in cross-linking filaments or anchoring other molecules. It is essential for growth.<ref>PMID:10339566</ref> <ref>PMID:11278681</ref> <ref>PMID:1541631</ref> <ref>PMID:17213332</ref> <ref>PMID:7503995</ref> <ref>PMID:9384578</ref>
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[[http://www.uniprot.org/uniprot/CALM_KLULA CALM_KLULA]] Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. [[http://www.uniprot.org/uniprot/SP110_YEAST SP110_YEAST]] Component of the spindle pole body (SPB) required for the proper execution of spindle pole body (SPB) duplication. Potential role in cross-linking filaments or anchoring other molecules. It is essential for growth.<ref>PMID:10339566</ref> <ref>PMID:11278681</ref> <ref>PMID:1541631</ref> <ref>PMID:17213332</ref> <ref>PMID:7503995</ref> <ref>PMID:9384578</ref>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Kluyveromyces lactis]]
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[[Category: Baker's yeast]]
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[[Category: Saccharomyces cerevisiae s288c]]
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[[Category: Candida sphaerica]]
[[Category: Klenchin, V A]]
[[Category: Klenchin, V A]]
[[Category: Rayment, I]]
[[Category: Rayment, I]]

Revision as of 22:59, 5 August 2016

Crystal structure of yeast calmodulin bound to the C-terminal fragment of spindle pole body protein Spc110

4ds7, resolution 2.15Å

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