Krebs cycle step 8
From Proteopedia
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| - | <h2>Step 8 of the Krebs cycle: Malate-Dehydrogenase</h2> | + | <h2>Step 8 of the Krebs cycle: [[Malate dehydrogenase|Malate-Dehydrogenase]]</h2> |
[[Image:malate.jpg]] | [[Image:malate.jpg]] | ||
| - | <p>Figure: Formation of | + | <p>Figure: Formation of Oxalacetate</p> |
<p>This final reaction closes the krebs cycle. here, L-malate is transformed into oxal acetate. The hydroxy | <p>This final reaction closes the krebs cycle. here, L-malate is transformed into oxal acetate. The hydroxy | ||
group of L-malate (in yellow) is oxidized to an α-keto group and the released protons are picked up by | group of L-malate (in yellow) is oxidized to an α-keto group and the released protons are picked up by | ||
NAD<sup>+</sup>, which then is reduced to NADH + H<sup>+</sup>.</p> | NAD<sup>+</sup>, which then is reduced to NADH + H<sup>+</sup>.</p> | ||
Current revision
Step 8 of the Krebs cycle: Malate-Dehydrogenase
Figure: Formation of Oxalacetate
This final reaction closes the krebs cycle. here, L-malate is transformed into oxal acetate. The hydroxy group of L-malate (in yellow) is oxidized to an α-keto group and the released protons are picked up by NAD+, which then is reduced to NADH + H+.
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Michal Harel, Verena Pietzner, Alexander Berchansky, Jaime Prilusky
