4rqm
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal structure of the SeMET BICC1 SAM Domain R924E mutant== |
| - | + | <StructureSection load='4rqm' size='340' side='right' caption='[[4rqm]], [[Resolution|resolution]] 1.75Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4rqm]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RQM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RQM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rqn|4rqn]]</td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rqm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rqm OCA], [http://pdbe.org/4rqm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rqm RCSB], [http://www.ebi.ac.uk/pdbsum/4rqm PDBsum]</span></td></tr> |
| - | [[ | + | </table> |
| - | [[Category: Bowie, J | + | == Disease == |
| + | [[http://www.uniprot.org/uniprot/BICC1_HUMAN BICC1_HUMAN]] Autosomal dominant polycystic kidney disease. Disease susceptibility is associated with variations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BICC1_HUMAN BICC1_HUMAN]] Putative RNA-binding protein. Acts as a negative regulator of Wnt signaling. May be involved in regulating gene expression during embryonic development.<ref>PMID:21922595</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bowie, J U]] | ||
[[Category: Cascio, D]] | [[Category: Cascio, D]] | ||
| + | [[Category: Leettola, C N]] | ||
| + | [[Category: P-body]] | ||
| + | [[Category: Polymerization]] | ||
| + | [[Category: Polymerization domain]] | ||
| + | [[Category: Protein binding]] | ||
| + | [[Category: Protein-protein interaction domain]] | ||
| + | [[Category: Sam domain]] | ||
Revision as of 02:25, 28 January 2016
Crystal structure of the SeMET BICC1 SAM Domain R924E mutant
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