2g1w

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|PDB= 2g1w |SIZE=350|CAPTION= <scene name='initialview01'>2g1w</scene>
|PDB= 2g1w |SIZE=350|CAPTION= <scene name='initialview01'>2g1w</scene>
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|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g1w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g1w OCA], [http://www.ebi.ac.uk/pdbsum/2g1w PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2g1w RCSB]</span>
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[[Category: trans-translation]]
[[Category: trans-translation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:59:26 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:10:41 2008''

Revision as of 00:10, 31 March 2008

Image:2g1w.gif


PDB ID 2g1w

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Ligands: , , ,
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1


Overview

The transfer-messenger RNA (tmRNA) pseudoknot PK1 is essential for bacterial trans-translation, a ribosomal rescue mechanism. We report the solution structure of PK1 from Aquifex aeolicus, which despite an unprecedented small number of nucleotides and thus an unprecented compact size, displays a very high thermal stability. Several unusual structural features account for these properties and indicate that PK1 belongs to the class of ribosomal frameshift pseudoknots. This suggests a similarity between the mechanism of programmed ribosomal frameshifting and trans-translation.

About this Structure

2G1W is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1: new insights into the recoding event of the ribosomal trans-translation., Nonin-Lecomte S, Felden B, Dardel F, Nucleic Acids Res. 2006 Apr 4;34(6):1847-53. Print 2006. PMID:16595798

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