2xii
From Proteopedia
(Difference between revisions)
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==CRYSTAL STRUCTURE OF AN ALPHA-L-FUCOSIDASE GH29 FROM BACTEROIDES THETAIOTAOMICRON IN COMPLEX WITH AN EXTENDED 9-FLUORENONE IMINOSUGAR INHIBITOR== | ==CRYSTAL STRUCTURE OF AN ALPHA-L-FUCOSIDASE GH29 FROM BACTEROIDES THETAIOTAOMICRON IN COMPLEX WITH AN EXTENDED 9-FLUORENONE IMINOSUGAR INHIBITOR== | ||
<StructureSection load='2xii' size='340' side='right' caption='[[2xii]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='2xii' size='340' side='right' caption='[[2xii]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2xii]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2xii]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_thetaiotaomicron"_distaso_1912 "bacillus thetaiotaomicron" distaso 1912]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XII OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XII FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TA9:9-OXO-N-[[(2R,3R,4R,5R,6S)-3,4,5-TRIHYDROXY-6-METHYL-PIPERIDIN-2-YL]METHYL]FLUORENE-1-CARBOXAMIDE'>TA9</scene>, <scene name='pdbligand=TYR:TYROSINE'>TYR</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TA9:9-OXO-N-[[(2R,3R,4R,5R,6S)-3,4,5-TRIHYDROXY-6-METHYL-PIPERIDIN-2-YL]METHYL]FLUORENE-1-CARBOXAMIDE'>TA9</scene>, <scene name='pdbligand=TYR:TYROSINE'>TYR</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wvt|2wvt]], [[2wvs|2wvs]], [[2wvu|2wvu]], [[2wvv|2wvv]], [[2xib|2xib]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wvt|2wvt]], [[2wvs|2wvs]], [[2wvu|2wvu]], [[2wvv|2wvv]], [[2xib|2xib]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alpha-L-fucosidase Alpha-L-fucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.51 3.2.1.51] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alpha-L-fucosidase Alpha-L-fucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.51 3.2.1.51] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xii OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xii RCSB], [http://www.ebi.ac.uk/pdbsum/2xii PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xii OCA], [http://pdbe.org/2xii PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xii RCSB], [http://www.ebi.ac.uk/pdbsum/2xii PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xii ProSAT]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2xii ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Bacillus thetaiotaomicron distaso 1912]] | ||
[[Category: Alpha-L-fucosidase]] | [[Category: Alpha-L-fucosidase]] | ||
| - | [[Category: Bacteroides thetaiotaomicron]] | ||
[[Category: Bueren, A Lammerts Van]] | [[Category: Bueren, A Lammerts Van]] | ||
[[Category: Davies, G J]] | [[Category: Davies, G J]] | ||
Revision as of 14:34, 4 August 2016
CRYSTAL STRUCTURE OF AN ALPHA-L-FUCOSIDASE GH29 FROM BACTEROIDES THETAIOTAOMICRON IN COMPLEX WITH AN EXTENDED 9-FLUORENONE IMINOSUGAR INHIBITOR
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