3op5
From Proteopedia
(Difference between revisions)
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==Human vaccinia-related kinase 1== | ==Human vaccinia-related kinase 1== | ||
<StructureSection load='3op5' size='340' side='right' caption='[[3op5]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='3op5' size='340' side='right' caption='[[3op5]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3op5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3op5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OP5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OP5 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=REB:[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENYL]ACETONITRILE'>REB</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=REB:[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENYL]ACETONITRILE'>REB</scene></td></tr> | ||
- | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VRK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VRK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3op5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3op5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3op5 RCSB], [http://www.ebi.ac.uk/pdbsum/3op5 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3op5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3op5 OCA], [http://pdbe.org/3op5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3op5 RCSB], [http://www.ebi.ac.uk/pdbsum/3op5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3op5 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
- | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3op5 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Human]] |
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Allerston, C K]] | [[Category: Allerston, C K]] |
Revision as of 15:06, 5 August 2016
Human vaccinia-related kinase 1
|
Categories: Human | Non-specific serine/threonine protein kinase | Allerston, C K | Arrowsmith, C H | Berridge, G | Bountra, C | Brenner, B | Chalk, R | Das, S | Delft, F von | Edwards, A M | Elkins, J M | Eswaran, J | Fedorov, O | Filippakopoulos, P | Gileadi, O | Keates, T | King, O | Knapp, S | Krojer, T | Rellos, P | Structural genomic | Savitsky, P | Uttarkar, S | Weigelt, J | Adenosine triphosphate | Amino acid sequence | Binding site | Catalytic domain | Model | Molecular | Molecular sequence data | Phosphotransferase | Protein conformation | Protein folding | Sgc | Surface entropy reduction | Transferase