This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3vfh
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==BlaC E166A CDC-1 Acyl-Intermediate== | ==BlaC E166A CDC-1 Acyl-Intermediate== | ||
<StructureSection load='3vfh' size='340' side='right' caption='[[3vfh]], [[Resolution|resolution]] 2.57Å' scene=''> | <StructureSection load='3vfh' size='340' side='right' caption='[[3vfh]], [[Resolution|resolution]] 2.57Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3vfh]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3vfh]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VFH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VFH FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD6:(2R)-5-METHYLIDENE-2-{(1R)-2-OXO-1-[(PHENYLACETYL)AMINO]ETHYL}-5,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC+ACID'>CD6</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD6:(2R)-5-METHYLIDENE-2-{(1R)-2-OXO-1-[(PHENYLACETYL)AMINO]ETHYL}-5,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC+ACID'>CD6</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3vff|3vff]], [[4ebi|4ebi]], [[4ebl|4ebl]], [[4ebm|4ebm]], [[4ebn|4ebn]], [[4ebo|4ebo]], [[4ebp|4ebp]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3vff|3vff]], [[4ebi|4ebi]], [[4ebl|4ebl]], [[4ebm|4ebm]], [[4ebn|4ebn]], [[4ebo|4ebo]], [[4ebp|4ebp]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaA, blaC, MT2128, MTCY49.07c, Rv2068c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaA, blaC, MT2128, MTCY49.07c, Rv2068c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr> |
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vfh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vfh RCSB], [http://www.ebi.ac.uk/pdbsum/3vfh PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vfh OCA], [http://pdbe.org/3vfh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3vfh RCSB], [http://www.ebi.ac.uk/pdbsum/3vfh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3vfh ProSAT]</span></td></tr> |
</table> | </table> | ||
| Line 15: | Line 16: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Beta-lactamase]] | [[Category: Beta-lactamase]] | ||
| - | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Mire, J A]] | [[Category: Mire, J A]] | ||
[[Category: Sacchettini, J C]] | [[Category: Sacchettini, J C]] | ||
Revision as of 08:17, 11 August 2016
BlaC E166A CDC-1 Acyl-Intermediate
| |||||||||||
