3rco
From Proteopedia
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==Crystal structure of a conserved motif in human TDRD7== | ==Crystal structure of a conserved motif in human TDRD7== | ||
<StructureSection load='3rco' size='340' side='right' caption='[[3rco]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='3rco' size='340' side='right' caption='[[3rco]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3rco]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3rco]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RCO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RCO FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TDRD7, PCTAIRE2BP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TDRD7, PCTAIRE2BP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rco OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rco RCSB], [http://www.ebi.ac.uk/pdbsum/3rco PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rco OCA], [http://pdbe.org/3rco PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3rco RCSB], [http://www.ebi.ac.uk/pdbsum/3rco PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3rco ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/TDRD7_HUMAN TDRD7_HUMAN]] The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TDRD7_HUMAN TDRD7_HUMAN]] Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis.<ref>PMID:21436445</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
[[Category: Bian, C]] | [[Category: Bian, C]] | ||
Revision as of 19:11, 11 August 2016
Crystal structure of a conserved motif in human TDRD7
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Categories: Human | Arrowsmith, C H | Bian, C | Bountra, C | Dong, A | Edwards, A M | Guo, Y | Lam, R | Li, Y | Min, J | Structural genomic | Walker, J R | Weigelt, J | Xu, C | Dna binding protein | Hlh motif | Sgc
