3w69

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==Crystal structure of human mdm2 with a dihydroimidazothiazole inhibitor==
==Crystal structure of human mdm2 with a dihydroimidazothiazole inhibitor==
<StructureSection load='3w69' size='340' side='right' caption='[[3w69]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3w69' size='340' side='right' caption='[[3w69]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LTZ:(5R,6S)-2-[((2S,5R)-2-{[(3R)-4-ACETYL-3-METHYLPIPERAZIN-1-YL]CARBONYL}-5-ETHYLPYRROLIDIN-1-YL)CARBONYL]-5,6-BIS(4-CHLOROPHENYL)-3-ISOPROPYL-6-METHYL-5,6-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE'>LTZ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LTZ:(5R,6S)-2-[((2S,5R)-2-{[(3R)-4-ACETYL-3-METHYLPIPERAZIN-1-YL]CARBONYL}-5-ETHYLPYRROLIDIN-1-YL)CARBONYL]-5,6-BIS(4-CHLOROPHENYL)-3-ISOPROPYL-6-METHYL-5,6-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE'>LTZ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MDM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MDM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w69 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w69 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3w69 RCSB], [http://www.ebi.ac.uk/pdbsum/3w69 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w69 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w69 OCA], [http://pdbe.org/3w69 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3w69 RCSB], [http://www.ebi.ac.uk/pdbsum/3w69 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3w69 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3w69" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==

Revision as of 10:23, 11 August 2016

Crystal structure of human mdm2 with a dihydroimidazothiazole inhibitor

3w69, resolution 1.90Å

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