2i9f
From Proteopedia
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|PDB= 2i9f |SIZE=350|CAPTION= <scene name='initialview01'>2i9f</scene>, resolution 2.00Å | |PDB= 2i9f |SIZE=350|CAPTION= <scene name='initialview01'>2i9f</scene>, resolution 2.00Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL | + | |LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= ORF7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11047 Equine arteritis virus]) | |GENE= ORF7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11047 Equine arteritis virus]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[1p65|1P65]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2i9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i9f OCA], [http://www.ebi.ac.uk/pdbsum/2i9f PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2i9f RCSB]</span> | ||
}} | }} | ||
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[[Category: Walsh, M.]] | [[Category: Walsh, M.]] | ||
[[Category: Wang, S.]] | [[Category: Wang, S.]] | ||
| - | [[Category: CL]] | ||
| - | [[Category: DTT]] | ||
| - | [[Category: GOL]] | ||
| - | [[Category: NA]] | ||
[[Category: assembly]] | [[Category: assembly]] | ||
[[Category: capsid]] | [[Category: capsid]] | ||
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[[Category: virus]] | [[Category: virus]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:41:16 2008'' |
Revision as of 00:41, 31 March 2008
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| , resolution 2.00Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , , , | ||||||
| Gene: | ORF7 (Equine arteritis virus) | ||||||
| Related: | 1P65
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Structure of the equine arterivirus nucleocapsid protein
Overview
Equine arteritis virus (EAV) is an enveloped positive-sense RNA virus belonging to the Arteriviridae family, which also includes the porcine pathogen PRRSV and is genetically and structurally related to the coronaviruses. EAV is an important equine pathogen that has caused significant economic losses to the horse-breeding industry and has been difficult to control. The EAV virion consists of a genome-containing nucleocapsid core made of nucleocapsid (N) protein surrounded by a lipid envelope containing several membrane proteins. Here, the crystal structure of the capsid-forming domain of the EAV N protein is presented at 2.0 A resolution. The dimeric N-protein structure is similar to the previously determined structure of the N protein from PRRSV, with most differences localized to the terminal helices and flexible loops. The N protein is organized as dimers of dimers in the crystal, which may reflect the arrangement of the protein in the viral nucleocapsid.
About this Structure
2I9F is a Single protein structure of sequence from Equine arteritis virus. Full crystallographic information is available from OCA.
Reference
Structure of the equine arteritis virus nucleocapsid protein reveals a dimer-dimer arrangement., Deshpande A, Wang S, Walsh MA, Dokland T, Acta Crystallogr D Biol Crystallogr. 2007 May;63(Pt 5):581-6. Epub 2007, Apr 21. PMID:17452783
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