2if4
From Proteopedia
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|ACTIVITY= | |ACTIVITY= | ||
|GENE= FKBP42, TWD1, UCU2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 Arabidopsis thaliana]) | |GENE= FKBP42, TWD1, UCU2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 Arabidopsis thaliana]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[2f4e|2F4E]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2if4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2if4 OCA], [http://www.ebi.ac.uk/pdbsum/2if4 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2if4 RCSB]</span> | ||
}} | }} | ||
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[[Category: tpr-like]] | [[Category: tpr-like]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:43:28 2008'' |
Revision as of 00:43, 31 March 2008
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| , resolution 2.85Å | |||||||
|---|---|---|---|---|---|---|---|
| Gene: | FKBP42, TWD1, UCU2 (Arabidopsis thaliana) | ||||||
| Related: | 2F4E
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of a multi-domain immunophilin from Arabidopsis thaliana
Overview
FKBP42 is a membrane-anchored immunophilin playing a critical role in morphogenesis and development of higher plants. We present the X-ray structure of the cytoplasmic portion of FKBP42 comprising both the FKBP-like domain and the TPR domain at 2.85 A resolution. The data shed light on the probable binding modes of key interaction partners, including HSP90 and two classes of ABC transporters. The resulting models provide a structural background for further investigation of the unique biological properties of this protein.
About this Structure
2IF4 is a Single protein structure of sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.
Reference
Crystal structure of a multi-domain immunophilin from Arabidopsis thaliana: a paradigm for regulation of plant ABC transporters., Granzin J, Eckhoff A, Weiergraber OH, J Mol Biol. 2006 Dec 8;364(4):799-809. Epub 2006 Sep 26. PMID:17045295
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