2j3p

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|PDB= 2j3p |SIZE=350|CAPTION= <scene name='initialview01'>2j3p</scene>, resolution 1.40&Aring;
|PDB= 2j3p |SIZE=350|CAPTION= <scene name='initialview01'>2j3p</scene>, resolution 1.40&Aring;
|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Chain+A'>AC1</scene>
|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Chain+A'>AC1</scene>
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|LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>
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|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
|ACTIVITY=
|ACTIVITY=
|GENE=
|GENE=
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|DOMAIN=
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j3p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j3p OCA], [http://www.ebi.ac.uk/pdbsum/2j3p PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2j3p RCSB]</span>
}}
}}
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[[Category: Kristensen, O.]]
[[Category: Kristensen, O.]]
[[Category: Kulahin, N.]]
[[Category: Kulahin, N.]]
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[[Category: SO4]]
 
[[Category: acidic fibroblast growth factor]]
[[Category: acidic fibroblast growth factor]]
[[Category: angiogenesis]]
[[Category: angiogenesis]]
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[[Category: mitogen]]
[[Category: mitogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:36:49 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:52:25 2008''

Revision as of 00:52, 31 March 2008


PDB ID 2j3p

Drag the structure with the mouse to rotate
, resolution 1.40Å
Sites:
Ligands:
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF RAT FGF1 AT 1.4 A


Overview

Fibroblast growth factors (FGFs) constitute a family of 22 structurally related heparin-binding polypeptides that are involved in the regulation of cell growth, survival, differentiation and migration. Here, a 1.4 A resolution X-ray structure of rat FGF1 is presented. Two molecules are present in the asymmetric unit of the crystal and they coordinate a total of five sulfate ions. The structures of human, bovine and newt FGF1 have been published previously. Human and rat FGF1 are found to have very similar structures.

About this Structure

2J3P is a Single protein structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

Structure of rat acidic fibroblast growth factor at 1.4 A resolution., Kulahin N, Kiselyov V, Kochoyan A, Kristensen O, Kastrup JS, Berezin V, Bock E, Gajhede M, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Feb 1;63(Pt, 2):65-8. Epub 2007 Jan 27. PMID:17277441

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