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4oop

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'''Unreleased structure'''
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==Arabidopsis thaliana dUTPase with with magnesium and alpha,beta-imido-dUTP==
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<StructureSection load='4oop' size='340' side='right' caption='[[4oop]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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The entry 4oop is ON HOLD until Apr 04 2016
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4oop]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OOP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OOP FirstGlance]. <br>
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Authors: Inoguchi, N., Bajaj, M., Moriyama, H.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DUP:2-DEOXYURIDINE+5-ALPHA,BETA-IMIDO-TRIPHOSPHATE'>DUP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ooq|4ooq]]</td></tr>
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Description: Arabidopsis thaliana dUTPase with with magnesium and alpha,beta-imido-dUTP
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dUTP_diphosphatase dUTP diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.23 3.6.1.23] </span></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oop FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oop OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4oop RCSB], [http://www.ebi.ac.uk/pdbsum/4oop PDBsum]</span></td></tr>
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[[Category: Moriyama, H]]
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</table>
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[[Category: Inoguchi, N]]
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== Function ==
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[[http://www.uniprot.org/uniprot/DUT_ARATH DUT_ARATH]] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP, preventing uracil incorporation into DNA.<ref>PMID:20227352</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: DUTP diphosphatase]]
[[Category: Bajaj, M]]
[[Category: Bajaj, M]]
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[[Category: Inoguchi, N]]
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[[Category: Moriyama, H]]
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[[Category: Dutp]]
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[[Category: Dutpase]]
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[[Category: Hydrolase]]
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[[Category: Hydrolysis]]

Revision as of 11:12, 8 April 2015

Arabidopsis thaliana dUTPase with with magnesium and alpha,beta-imido-dUTP

4oop, resolution 1.50Å

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