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4ryh

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'''Unreleased structure'''
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==Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM59==
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<StructureSection load='4ryh' size='340' side='right' caption='[[4ryh]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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The entry 4ryh is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4ryh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RYH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RYH FirstGlance]. <br>
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Authors: Deng, X., Phillips, M.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D59:N-(3,5-DICHLOROPHENYL)-2-METHYL-3-NITROBENZAMIDE'>D59</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ORO:OROTIC+ACID'>ORO</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_dehydrogenase_(quinone) Dihydroorotate dehydrogenase (quinone)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.5.2 1.3.5.2] </span></td></tr>
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Description: Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM59
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ryh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ryh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ryh RCSB], [http://www.ebi.ac.uk/pdbsum/4ryh PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PYRD_PLAF7 PYRD_PLAF7]] Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
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__TOC__
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</StructureSection>
[[Category: Deng, X]]
[[Category: Deng, X]]
[[Category: Phillips, M]]
[[Category: Phillips, M]]
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[[Category: Alpha/beta barrel]]
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[[Category: Fmn]]
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[[Category: Mitochondrial membrane]]
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[[Category: Oxidoreductase]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]

Revision as of 12:23, 13 May 2015

Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM59

4ryh, resolution 2.30Å

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