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4oeq

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Current revision (13:06, 1 April 2015) (edit) (undo)
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==Crystal structure of the ZO-1 PDZ1 domain in complex with the 7-mer Claudin2 C-terminal tail==
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#REDIRECT [[4yyx]] This PDB entry is obsolete and replaced by 4yyx
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<StructureSection load='4oeq' size='340' side='right' caption='[[4oeq]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4oeq]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OEQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OEQ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4oeo|4oeo]], [[4oep|4oep]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oeq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oeq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4oeq RCSB], [http://www.ebi.ac.uk/pdbsum/4oeq PDBsum]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ZO1_HUMAN ZO1_HUMAN]] The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.<ref>PMID:21240187</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Lavie, A]]
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[[Category: Nomme, J]]
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[[Category: Cell adhesion]]
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[[Category: Claudin]]
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[[Category: Maguk]]
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[[Category: Pdz1]]
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[[Category: Scaffolding]]
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[[Category: Tight junction assembly]]
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Current revision

  1. REDIRECT 4yyx This PDB entry is obsolete and replaced by 4yyx

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