2jhc

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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jhc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jhc OCA], [http://www.ebi.ac.uk/pdbsum/2jhc PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2jhc RCSB]</span>
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[[Category: Stuart, D I.]]
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[[Category: Sutton, G.]]
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[[Category: GUN]]
 
[[Category: core protein]]
[[Category: core protein]]
[[Category: guanylyltransferase]]
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[[Category: virion protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:58:15 2008''

Revision as of 00:58, 31 March 2008


PDB ID 2jhc

Drag the structure with the mouse to rotate
, resolution 3.00Å
Sites:
Ligands:
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE


Overview

Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series of four chemical reactions. Some viruses achieve this using a single molecule; the crystal structure of such an enzyme from bluetongue virus reveals an elongated modular architecture that provides a scaffold for an assemblage of active sites, two contributed by a domain of novel structure.

About this Structure

2JHC is a Single protein structure of sequence from Bluetongue virus 10 (isolate usa). Full crystallographic information is available from OCA.

Reference

Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:17417654

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